Monmouth Building renovation

CWRU, Clinic projects come close to completion

Cleveland’s downtown may possess its historic core and central business district, but several massive developments are solidifying Greater University Circle’s status as one of the most important job centers in Northeast Ohio.

$300M CWRU project at heart of growing University Circle

Harrison Whittaker / December 22, 2025

In the three years since Case Western Reserve University (CWRU) first announced plans for a new Interdisciplinary Science and Engineering Building (ISEB), the $300 million donor-supported project has seen substantial progress.

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